Description
Product Characteristics: This gene encodes a protein that functions as a transcriptional activator that binds specifically to non-methylated CpG motifs through its CXXC domain. The protein is a component of the SETD1 complex, regulates gene expression and is essential for vertebrate development.,CXXC1,2410002I16Rik,5830420C16Rik,CFP1,CGBP,HsT2645,PCCX1,PHF18,SPP1,ZCGPC1,hCGBP,Epigenetics & Nuclear Signaling,Transcription Factors,Chromatin Remodeling,CXXC1
Target Information: Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression (Carlone and Skalnik, 2001 [PubMed 11604496]).[supplied by OMIM, Mar 2008]